Beyond the putative role of nonhuman Neu5Gc, there is a potential molecular link between diet, autoreactive antibodies, and the progression of human cancer. Let me offer one final tidbit on the evolving Neu5Gc story: the potentially deadly toxin produced by E. coli O157:H7, which causes hemolytic uremic syndrome that can shut down children's kidneys, actually attaches to Neu5Gc when we consume animal products. The assimilation of dietary Neu5Gc creates high affinity receptors on the human gut lining and kidney blood vessels, conferring susceptibility to the gastrointestinal and systemic toxicities of the E. coli toxin. Ironically, the same foods rich in Neu5Gc are the most common source of contamination with these toxin-producing E. coli. So, meat provides us with the receptors for the very toxins it may contain. It's like a gunman handing us our own bull's eye. Therefore, there are both long and short-term consequences. Taken together, these findings suggest a two-hit process in the pathogenesis of human E. coli-induced disease. First, humans eat Neu5Gc-rich food, leading to the incorporation of Neu5Gc on the surfaces of their cells. Second, when exposed to a toxin-producing strain, the produced toxin will be able to bind to the intestinal epithelial cells, perhaps causing acute gastrointestinal symptoms and eventually damaging endothelial cells in other organs like the kidney, thereby causing Hemolytic Uremic Syndrome (HUS). Neu5Gc-rich foods not only sensitize human tissues to the toxin but also simultaneously increase the likelihood of infection with toxin-producing E. coli. These pathogens are usually found in the intestines of livestock and commonly enter the human food chain through fecal contamination. Thus, those who consume large amounts of these types of foods may unknowingly prepare their bodies for damage by a toxin-producing organism that contaminates their next meal of the same food types. The researchers question whether this is poetic justice for meat-eaters....
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Foreign daily allowance Form: What You Should Know
But if you qualify for FEW compensation you must be paid in Foreign Earned Income Exclusion of Income (FIE) — Secretary of the Treasury You can't use FIE to exclude income without a work-related plan. It can be used to exclude your Foreign Exemption — IRS Nonresident Aliens, Foreign Earned Income Exclusion (FIE) — Secretary of the Treasury If you are a nonresident alien, you must be paid to work in the U.S. In such case, the U.S. does not treat you as a resident alien. Therefore, you are not subject to U.S. tax for any U.S. source income you include on this form in computing foreign source income. 2022 Instructions for Form 2555 — IRS 2023 Instructions for Form 2555 — IRS The nonresident alien may be eligible to the FIE even if you are engaged in a different business that does not generate U.S. sales. 2024 Instructions for Form 2555 — IRS You are eligible for FIE if you are a qualifying child under age 21 who is employed by a parent for at least half of the workweek. You can choose to report your FIE income to the IRS rather than to the foreign country. You can file the FIE return and pay the applicable FIE withholding tax only to the IRS. Furthermore, you can be taxed only on your foreign earned income and wages. In addition, no other tax is imposed on your foreign earned income. Foreign Earned Income Exclusion (FIE) — Secretary of the Treasury Nonresident aliens, foreign income, and foreign taxes on income. If you're a foreign investor, you can use the Form 1099-INT, Statement of Certain Foreign Income and Taxes Paid to the U.S., to exclude this income from your gross income. Foreign Income Tax Return for Individuals Not Located in the United States Foreign Income Tax Return for Individuals Not Located in the United States. U.S. source income may be subject to U.S. tax when it is includible in the gross income of a nonresident alien and paid or accrued to an individual who is not a resident of the United States. Foreign earned income can be subject to U.S. tax on its nontaxable portions. As a result, income is effectively withdrawn when the nonresident alien or his or her spouse has earned their ordinary income.
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